Title: GI Secretions and Their Clinical Relevance
Authors: Suzan Kamel- ElSayed, VMD, PhD; Richard Sabina, PhD; David M. Thomas, PhD; Gustavo Patino, MD, PhD and Sarah Lerchenfeldt, Pharm D
Affiliations: Oakland University William Beaumont School of Medicine
Resources available with this module: Application Exercise
Context: Gastroenterology and Hepatobiliary Organ System Course
This TBL module was developed for second-year medical students enrolled in a required Gastroenterology and Hepatobiliary Organ System Course. It was designed to cover foundational concepts for the physiology of gastrointestinal (GI) secretion and its regulation, as well as the pathophysiology, causes, and diagnoses of two important GI diseases (cystic fibrosis and Zollinger-Ellison syndrome). This TBL module was offered during the 4th week of a five-week course.

Required ReadingSession objectives and advanced the preparatory material (a 21 page reading assignment) were provided to students one week prior to the scheduled TBL module. External resources can be used during application exercise.
Objectives

• Describe the paracrine, endocrine and neural regulation of gastrointestinal secretion.
• Demonstrate how paracrine, endocrine and neural factors can coordinate to regulate gastrointestinal secretory functions.
• Compare sympathetic and parasympathetic innervations and their effects on salivary gland secretion.
• Distinguish between the pathophysiologic mechanisms of two different clinical problems that are associated with secretory functions of the gastrointestinal system.
• Engage the material by critically evaluating its content and employing peer teaching during the session.
• Participate in the TBL in a professional and respectful manner.

For more information on this, and more, modules available in the Resource Bank, please visit the Resource Portal.